WebJan 1, 2011 · In humans, SCD1 expression was found to be elevated in skeletal muscle after endurance exercise, which prevented fatty acid-induced insulin resistance . This effect was attributed to the enhanced lipogenic capacity that partitions FFA and their bioactive metabolites into neutralized lipids such as TG, thus reducing the proinflammatory … WebJan 14, 1999 · Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (608370), have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2.
SCD1 deficiency exacerbates osteoarthritis by inducing …
WebValidated for WB, IP, IHC, IF. Highly specific and rigorously validated in-house, SCD1 (C12H5) Rabbit Monoclonal Antibody (CST #2794) ... Human, Mouse. Source / Purification. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu35 of mouse SCD1. WebImmunohistochemical analysis of paraffin-embedded human adipose tissue within cardiac muscle tissue labeling SCD1 with ab236868 at 1/2000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) ready to use. Positive staining in human adipose cells in cardiac muscle (PMID: 15907797) is observed. Counter stained with hematoxylin. nancy drew curse of blackmoor manor trailer
Human SCD (SCD1) knockout HeLa cell line (ab265220)
Stearoyl-CoA desaturase (SCD; EC 1.14.19.1) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity an… WebMar 21, 2024 · SCD (Stearoyl-CoA Desaturase) is a Protein Coding gene. Diseases associated with SCD include Non-Alcoholic Fatty Liver Disease and Abdominal Obesity … WebHere we report the 3.25-Å crystal structure of human SCD1 in complex with its substrate, stearoyl-coenzyme A, which defines the new SCD1 dimetal catalytic center and reveals … megaphone brands activism