WebDec 26, 2024 · If conversion requires an initial haloperidol decanoate dosage >100 mg, administer in 2 injections (i.e., administer a maximum initial dose of 100 mg followed by the balance in 3–7 days); however, some clinicians have converted therapy to decanoate using a higher initial dose.
Long-Acting Injectable Antipsychotic Medications and …
WebApr 1, 2006 · Patients were given a loading dose of about 20 times their oral maintenance dose in divided injections during the first two weeks of conversion to depot medication. … WebMar 1, 2024 · Hsu (2013) 12 reported the case of a 39-year-old Chinese female with a history of schizophrenia who developed tardive dyskinesia (TD) following the discontinuation of depot haloperidol and initiation of INVEGA SUSTENNA. The patient was treated with depot haloperidol (40 mg/month) for 9 months but continued to experience prominent … free pdf mags download
A loading-dose strategy for converting from oral to depot …
WebInitial dose (mg) Frequency (hours) Maximum initial dose per 24 hours (mg) Time to peak plasma concentration (hours) Notes: First-generation agents: Haloperidol: Short-acting lactate injection: IM, IV: 2 to 5: 0.5 to 2* 20 ¶ 0.5 to 1: Sedation, hypotension and prolongation of QTc interval more pronounced with injection. ↑ EPS risk. Oral ... WebMedication Dosing Table ATYPICAL Atypical First Dose Titration Range Schedule clozapine 12.5 mg. (½ a 25 mg tab) ... haloperidol 5 – 15 mg /day haloperidol D 50 – 200 mg/ 3- 4 weeks thioridazine 300 – 800 mg/day ... Overlap old antipsychotic with new antipsychotic with new antipsychotic by 1-3 weeks, clozapine ... WebRodents given 2 to 20 times the usual maximum human dose of haloperidol by oral or parenteral routes showed an increase in incidence of resorption, reduced fertility, delayed delivery and pup mortality. No teratogenic effect has been reported in rats, rabbits or dogs at dosages within this range, but cleft palate has been observed in farmers market san clemente ca