Growth arrest-specific gene 6 gas6
WebMechanistically, corticosterone acts on the dermal papillae to suppress the expression of Gas6, a gene that encodes the secreted factor growth arrest specific 6. Restoring … WebGrowth-arrest specific gene 6 (Gas6) is a vitamin K-dependent growth factor for mesangial and epithelial cells. To investigate whether Gas6 is essential for progressive glomerular injury, we constructed Gas6(-/-) mice and examined the role of Gas6 in accelerated nephrotoxic nephritis (NTN), a model of progressive glomerulonephritis.
Growth arrest-specific gene 6 gas6
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WebJan 22, 2007 · The product of growth arrest-specific gene 6 (Gas6) is a vitamin K dependent protein that is secreted by leucocytes and endothelial cells in response to … WebNov 4, 2024 · Gas6 can bind to all three members of the TAM family, whereas protein S binds only to MER and TYRO3. The affinity of Gas6 for AXL is 3–10 times higher than that for the other two members in the family [8, 58]. Gas6 is encoded by growth arrest-specific gene 6 (Gas6) and belongs to the vitamin K-dependent protein family .
WebWe aimed to investigate the performance of Gas6 plasma levels at admission to predict the risk of mortality in a cohort of septic (PDF) Growth arrest-specific gene 6 (GAS6) as an intra-hospital mortality predictor for patients in septic shock P. Eggimann - Academia.edu WebBesides, knockdown of LINC00565 can induce cell cycle arrest in G0/G1 phase. In addition, in vivo assay showed that low expression of LINC00565 inhibited the growth of OC. Further study found that LINC00565 knockdown markedly downregulated the protein …
WebApr 2, 2024 · Growth arrest-specific 6 (GAS6) is a major ligand of AXL and its binding is essential for AXL phosphorylation and the activation of signal transduction . ... Expression of the growth arrest-specific gene 6 (GAS6) in leukemia and lymphoma cell lines. Leuk Res. 1999;23:643–51. CAS PubMed Google Scholar ... WebTAM:包括TYRO3、AXL和MER,配体为GAS6(growth-arrest-specific 6)和protein S。调节免疫。 ... Abl:包括ABL1(c-ABL) 和ABL2(也称为ABL-related gene,ARG)。在95%的慢性髓系白血病患者中,癌细胞会发生染色体异位,产生费城染色体,导致ABL1 ...
WebGrowth arrest specific gene 6 (Gas6) is involved in this process, bridging phosphatidylserine residues on the surface of apoptotic cells to the Axl/Mer family of tyrosine kinases which stimulate phagocytosis. Animals with mutations or loss of these receptors exhibit phenotypes reflective of impaired phagocytosis and a hyperactive immune response.
WebBesides, knockdown of LINC00565 can induce cell cycle arrest in G0/G1 phase. In addition, in vivo assay showed that low expression of LINC00565 inhibited the growth of OC. Further study found that LINC00565 knockdown markedly downregulated the protein expressions of CyclinD1, CyclinE1 and CDK4, but upregulated the expression of P16 and P21. island by south carolinaWebLenti ORF particles, GAS6 (mGFP-tagged) - Human growth arrest-specific 6 (GAS6), transcript variant 1, 200ul, >10^7 TU/mL Supplier Page. ... NCBI Full Gene Name … island cabana bar and ship storeWebPurpose of review: Growth arrest-specific gene 6 (Gas6) belongs to the family of vitamin K-dependent coagulation proteins, but in contrast to its other members, has only a limited role in hemostasis. Instead, Gas6 plays a prominent role in conditions of injury, inflammation and repair. Gas6 amplifies the activation of various cell types including endothelial cells … keypad softwareWebEnter the email address you signed up with and we'll email you a reset link. keypad split screenWebApr 4, 2024 · Orthologous to human GAS6 (growth arrest specific 6). [provided by Alliance of Genome Resources, Apr 2024] Other designations. growth arrest-specific protein 6, … keypad smartphone 2022WebNov 16, 2015 · Growth arrest–specific 6 (GAS6) is upregulated in failing human hearts, pressure overload–induced murine hypertrophic hearts, and angiotensin II–treated hypertrophic cardiomyocytes. For the first time, GAS6 is shown to accelerate the development of pressure overload–induced cardiac hypertrophy, fibrosis, and heart failure. island cabinet 18 inch depthWebFeb 19, 2008 · Growth arrest-specific gene 6 (Gas6), identified in 1995, acts as the ligand to the Axl/Tyro3 family of tyrosine kinase receptors and exerts mitogenic activity when … keypad smartphone 2015