WebMar 7, 2024 · Cryptococcus neoformans is one of the leading causes of invasive fungal infections worldwide. Cryptococcal meningoencephalitis is the main challenge of antifungal therapy due to high morbidity and mortality rates, especially in low- and middle-income countries. ... Cryptococcus neoformans urease affects the outcome of intracellular … WebApr 5, 2024 · Our group demonstrated that cryptococcal urease is a factor that strongly enhances crossing of C. neoformans from the blood into the brain, while another recent study demonstrated that ...
Urease Test: Principle, Procedure, Results • Microbe Online
WebMore Information. Cryptococcosis is a pulmonary or disseminated infection acquired by inhalation of soil contaminated with the encapsulated yeasts Cryptococcus neoformans or C. gattii. Symptoms are those of pneumonia, meningitis, or involvement of skin, bones, or viscera. Diagnosis is clinical and microscopic, confirmed by culture or fixed ... WebUrea hydrolysis and consequent production ammonia are detected by a chemical reaction producing a blue phenol compound (indophenol blue). Three hundred and three yeast … ostentatious display of learning
Diagnosis and Testing of C. gattii Infection Fungal …
WebJun 15, 2024 · Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with macrophages is a key event determining the outcome of infection. Urease is a major virulence factor in C. neoformans but its role during macrophage interaction has not been characterized. Consequently, we analyz … WebThe investigation of urease activity in C. neoformans showed that the addition of eugenol (125 µg/mL) and fluconazole (8 µg/mL) to the urea medium culture decreased the urease activity of C. neoformans, compared to that in the controls. The inhibition zone diameters of eugenol-treated, fluconazole-treated, and non-treated control groups were ... WebJun 15, 2024 · Abstract. Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with macrophages is a key … ostentatious in chinese